UK Community Advisory Board (UK-CAB)
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    • Clinical trials – a guide for CAB members (page 19)

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    • A protocol also describes the study’s “endpoints.” Endpoints are the things that will be measured in order to see which treatment works better (to compare the treatment groups).
    • In the example above, the endpoint is HIV infection in infants whose mothers were enrolled in a study and received either Medicine A or Medicine B to lower the risk of mother-to-child transmission of HIV infection. Researchers compare how many infants were infected with HIV despite the treatment. Were there more infections in Group A or Group B?